Is there any difference in how these two options will act in searches, mouse over, et. al.? ....
Orthodox Bishop Hilarion Alfeyev: "To be a theologian means to have experience of a personal encounter with God through prayer and worship."
I assume you are showing a screenshot of the label editor.
The first item in the list is just a text field. You will only be able to match that with text-type comparisons. The other item is a Bible reference. You can use standard Bible reference intersection matching.
Thank you Andrew. That is what I suspected