Warning - OSX beta (but probably not relevant)
Running Logos in 'Full Screen' and open at Home Page.
Click on icon to open Layout and...

I did notice that the floating panels associated with this layout opened in a separate space albeit on the same monitor - this is a great improvement over opening behind a panel in 'Full Screen'.
The situation is recoverable by coming out of 'Full Screen' at which point the layout expands to fill the screen and then re-entering 'Full Screen' but now, of course the workspace has been repositioned.