For years, I've used Adobe Garamond Pro for my primary resource font, even though much of the transliterated characters seemed wonky. I liked the classic feel of the font, so I just dealt with it.
Today, I was reading through a book that used a lot of transliteration (Heiser's Demons), and my reading experience was particularly hindered by the font's wonkiness, so I decided to try out the Default resource font. It's a much better reading experience for sure! The left is the Default font and the right is Adobe Garamond Pro.

That being said, are there other fonts you use for your resources that handle transliterated characters well or do you all just stick with the default font?