For the last couple of mornings, since moving to the latest beta (Logos Bible Software 4.0b (4.10.4.7689)), L4Mac had ground to a halt within a couple of minutes, with the spinning disc working over time!
I happened to look using Activity Monitor and saw that L4Mac was using 1.5 Gb of real memory (not the indexer, L4Mac).
If I then force quit L4Mac and re-launched it, it would launch more quickly and settle down at bout 250Mb of real memory, which is what I would expect of a handful of bibles, commentaries and note files. The speed of L4Mac seemed then to be good for the rest of my session. The real memory use did continue to rise without my opening any new resources but I could ascribe that to caching of pages as I moved around the resources, and the extra memory use would have taken all day to become a problem.
I wonder if anybody else has noticed this? If you have a slow L4Mac, try force quit and re-launchof L4Mac (not of the Mac itself).