We have a growing number of new users joining us in the Forums - let's post screenshots of our favorite Layouts that we have put together through the years. We may give examples in our own Layouts of what a new user would be looking for, but hasn't yet discovered.
I like keeping my Main Layout with multiple Bibles, a few Commentaries, Passage Guide, Bible Word Study, Power Lookup and Copy Bible Verses all linked via Link Set. At times I add in the Exegetical Guide.