I have a feeling that this may be related to bug report Rosie did on the Biblical places not opening Google Maps.
Clicking on my article on my Home Page will not open IE and take me to the web page. This works as expected on my SR2 installation. It throws the following error:
2010-01-11 07:35:38.1177 1 Info HyperlinkUtility Unable to launch default browser for http://blog.logos.com/archives/2010/01/morris_how_do_i.html: No application is associated with the specified file for this operation